![]() This modification was supposed to be polygenic as several phenotypes differing in their warm tone and countershading were observed, ranging from a classical golden ticked phenotype to a ‘copper’ phenotype characterized by a red mantle with marked ivory belly and ivory spots on the uppersides of the paws (Figure 1a–d). In British cats, breeders from Germany and Russia have reported since the 2010s a coat modification that is distinct from the known golden shaded (Vella et al., 1999) and golden ticked phenotypes (Lyons et al., 2021). These modifications, called sunshine and extreme‐sunshine, are similar to the golden modification of tigers (Xu et al., 2017). In the Siberian cat breed, two variants were identified in the CORIN (Corin, serine peptidase) gene, a suppressor of the ASIP (agouti signaling protein) pathway (Enshell‐Seijffers et al., 2008) that causes golden coat modifications characterized by enlarged subapical pheomelanin bands in hairs and reduced dark tips (Abitbol et al., 2022 Beauvois et al., 2021). We propose that this third CORIN:c.2425C>T variant represents the wb BSH ( British recessive wideband) allele in the domestic cat. Finally, genotyping of 218 cats from 12 breeds failed to identify carriers in cats from other breeds. All 30 copper cats were T/T homozygous for the variant, which was also found in 20 C/T heterozygous British control cats but was absent in 340 cats from the 99 Lives dataset. ![]() This nonsense CORIN:c.2425C>T variant, located in CORIN exon 19, was predicted to produce a truncated CORIN protein – CORIN:p.(Arg809Ter) – that would lack part of the scavenger receptor domain and the trypsine‐like serine protease catalytic domain. Segregation of the variant was consistent with recessive inheritance. A homozygous CORIN:c.2425C>T nonsense variant was identified in copper British cats. Within that region, we identified CORIN (Corin, serine peptidase) as the strongest candidate gene, since two CORIN variants have previously been identified in Siberian cats with a golden phenotype. A single candidate region was identified using a genome‐wide association study. Pedigree analyses revealed an autosomal recessive inheritance pattern. This modification restricted eumelanin to the tip of the tail and hairs showed a wideband modification. In the British feline breed a golden coat modification, called light‐gold, akita or copper, was reported by breeders during the 2010s.
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